Economia
NH TherAguix Announces Publication of Groundbreaking Study on AGuIX® Nanoparticles Enhancing Cervical Cancer Treatment
PRESS RELEASE
NH TherAguix Announces Publication of Groundbreaking Study on AGuIX® Nanoparticles Enhancing Cervical Cancer Treatment
Paris, France, Wednesday July 3 , 2024 – NH TherAguix (NHT), a phase II clinical-stage biotechnology company specializing in the development of novel nanomedicine solutions for precision radiotherapy in oncology, today announced the publication of a pioneering study in American Chemical Society (ACS) Nano , a high impact factor journal. The study, titled "Theragnostic gadolinium-based nanoparticles safely augment X-ray radiation effects in patients with cervical cancer" , provides compelling evidence supporting the use of AGuIX® nanoparticles to selectively enhance the effectiveness of radiotherapy in cervical cancer treatment.
AGuIX®: A nanodrug capable of improving the precision and effectiveness of radiotherapy
The culmination of over a decade of research, AGuIX® nanoparticles are designed to meet the critical medical need for more effective cancer treatments, including advanced cervical cancer. These gadolinium-based nanoparticles enhance MRI contrast, allowing for precise tumor visualization, and significantly amplify the radiation dose delivered to tumor tissues, thereby improving the efficacy of radiotherapy.
Study Highlights:
Dr. Olivier de Beaumont, CMO of NH TherAguix, emphasized the significance of these findings: "This study marks a significant advancement in the use of AGuIX® as a novel option for cancer treatment. The ability to quantify AGuIX® concentration in correspondence with tumor response signals with high precision opens new avenues for personalized medicine in oncology using companion MRI-based information."
Vincent Carrère, CEO of NH TherAguix, commented: "We are thrilled to announce this important publication in ACS Nano . I would like to thank the teams at IGR, especially Professors C. Chargari and E. Deutsch, for this remarkable clinical and translational work. It highlights the transformative potential of AGuIX® in enhancing radiotherapy for cervical cancer patients. These promising results reinforce our commitment to advancing innovative cancer treatments and improving patient outcomes."
About NH TherAguix: www.nhtheraguix.com
NH TherAguix is a late-stage biotech company developing AGuIX® to treat tumors and metastases in patients undergoing radiotherapy. It is estimated that approximately 60% of cancer patients receive radiotherapy. AGuIX® is currently being assessed in multiple Phase II randomized trials across various cancer types, including brain metastases, glioblastoma, and pancreatic and lung cancers.
To date, over 190 patients have been treated with AGuIX®. This innovation is protected by 18 patent families and has been extensively tested in various preclinical models, with results published in more than 80 high-impact publications.
NH TherAguix was established in 2015 following 10 years of academic research that led to the invention of AGuIX® and the discovery of its radiosensitizing effect. The company has raised approximately €40m of funds, including a €13m Series A in 2019 led by Bpifrance with Arbevel, Omnes, and Supernova.
Media contacts:
NH TherAguix
NewCap - Arthur Rouillé
arouille@newcap.fr
+33 (0)1 44 71 00 15
2321 Rosecrans Avenue. Suite 2200
90245 El Segundo Stati Uniti