Salute e Benessere
Oncoinvent Announces First Patient Dosed in its Phase 2 Clinical Trial of Radspherin® in Ovarian Cancer Patients
The Phase 2 trial (NCT06504147) is a randomized controlled study assessing the efficacy and safety of Radspherin® in patients with peritoneal metastasis from ovarian cancer. The primary objective is to compare PFS between patients who receive Radspherin® after complete surgical resection following pre-operative chemotherapy, and patients who only undergo pre-operative chemotherapy and surgery. The study is being conducted at six centers in the US, UK, Norway , Spain and Belgium . Positive Phase 1/2a data from the safety interim analysis demonstrated that Radspherin® was well tolerated with no dose-limiting toxicity observed at the recommended dose of 7MBq.
Oncoinvent AS is a clinical stage, radiopharmaceutical company developing innovative treatments for solid cancers. The technology platform is focused on the use of alpha-emitting radionuclides to deliver powerful radiation directly to cancer cells. The Company's lead product candidate, Radspherin , is being advanced through clinical development by a carefully composed team with experience from all stages of radiopharmaceutical development. Internal manufacturing and supply chain capabilities have been established, which now have the capacity to supply Radspherin for multi-center phase 2 clinical studies. For additional information, please visit www.oncoinvent.com
Radspherin is an investigational radiopharmaceutical designed for the local treatment of cancer that has spread to body cavities. It consists of billions of tiny calcium carbonate microparticles containing the radioactive material radium-224. The mode of action is the targeted delivery of alpha-particles, a highly potent form of radiation. Radspherin is being investigated in ongoing clinical studies to treat peritoneal metastases from ovarian and colorectal cancer; it is administered intraperitoneally after surgical resection and removal of all macroscopic tumors.
All statements other than statements of historical facts contained in this press release are forward-looking statements and are not a representation that Oncoinvent's plans, estimates, or expectations will be achieved. These forward-looking statements represent Oncoinvent's expectations as of the date of this press release, and Oncoinvent disclaims any obligation to update the forward-looking statements. These forward-looking statements are subject to known and unknown risks and uncertainties that may cause actual results to differ materially, including with respect to whether the results of clinical or other studies will support the use of our product offerings, the impact of results of such studies, our expectations of the reliability, accuracy and performance of our tests, or of the benefits of our tests and product offerings to patients, providers and payers.
Oystein Soug , Chief Executive Officer
Email: soug@oncoinvent.com
Tore Kvam , Chief Financial Officer
Email: kvam@oncoinvent.com
IR enquiries:
Courtney Mogerley , Precision AQ
Email: Courtney.Mogerley@precisionaq.com
This information was brought to you by Cision http://news.cision.com
The following files are available for download:
View original content: https://www.prnewswire.co.uk/news-releases/oncoinvent-announces-first-patient-dosed-in-its-phase-2-clinical-trial-of-radspherin-in-ovarian-cancer-patients-302272777.html