Bridge to Life Ltd. Achieves Global Milestone Using Hypothermic Oxygenated Perfusion (HOPE) and VitaSmart™ System

"We are proud to be the liver transplantation center that has reached this milestone for Bridge to Life," commented Russell Bolton, Head of Liver Services, UHB Liver Services Unit. "As one of the largest transplantation centers in the UK, providing a comprehensive range of hepatology (liver medicine), liver surgery, and liver transplantation services to our patients, UHB has been at the forefront of adopting new technologies that can make more livers available to patients in need," he added.

HOPE Technology: Optimizing Organ Viability

The HOPE technique cools donor livers to temperatures between 4°C and 12°C, reducing their metabolic rate to about 10% of normal. During this phase, the VitaSmart^™ system delivers oxygen-rich perfusion to the dormant organ, re-energizing its mitochondria—the cell's powerhouse—before transplantation. This pre-transplant conditioning helps minimize the risk of reperfusion injury, a major contributor to post-transplant complications.

With this milestone, Bridge to Life continues to lead innovation in organ preservation, enhancing transplant outcomes and meeting the urgent need for viable donor organs worldwide.

About Bridge to Life Ltd
Bridge to Life Ltd is a market leader in organ preservation solutions, offering premier products such as Belzer UW^®, EasiSlush^® and the VitaSmart Machine Perfusion System. With a strong focus on product quality, innovation and accessibility, the company serves and partners with leading Transplant Centers and Organ Procurement Offices globally.

¹ Number of perfusions is based on liver perfusions sets sold through October 31, 2024

² VitaSmart is CE Marked and available for sale in several markets outside of the United States. VitaSmart is not approved for sale in the US.

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