Italian Studies Confirm Safety of HOPE (Hypothermic Oxygenated PErfusion) for Liver Transplantation and Value of HOPE in Identifying Biomarkers for Assessing Liver Viability

"Our academic research centre has been at the forefront of evaluating the impact of HOPE in several aspects of liver transplantation," said Dr Damiano Patrono, MD, Liver Transplant Unit, AOU Città della Salute e della Scienza di Torino, Italy and principal investigator of the three trials. "We continue to be impressed with the value that the use of HOPE brings to increasing the supply of available livers for transplantation, potentially improving access for those in need of livers and reducing waiting time for transplantation," he further commented.

"These Italian studies are further support for the value that HOPE can contribute to the transplantation community worldwide," commented Don Webber, CEO and President of Bridge to Life Ltd., a leading provider of transplant solutions and a sponsor of the studies. "We are in the final stages of assessing the 1-year follow-up results of our HOPE Trial in the U.S. and look forward to bringing this innovative technology to U.S. transplant centers, organ procurement organizations, and, most importantly, to patients in need of viable livers," he added.

The three presentations include:

Outcomes of redo-liver transplantation using hypothermic oxygenated machine perfusion: a multicentre cohort study (REDO-HOPE), ID #373, D. Patrono (General Surgery 2U - Liver Transplant Unit, AOU Città della Salute e della Scienza di Torino), et al

Hypothermic oxygenated machine perfusion is not associated with an increased risk of infection in the recipient: A retrospective single-centre cohort study, ID #453, S. Corcione (General Surgery 2U - Liver Transplant Unit, AOU Città della Salute e della Scienza di Torino), et al

Circulating cell-free DNA in liver transplantation: A pre- and post-transplant biomarker of graft dysfunction, ID #828, T. Carradori (General Surgery 2U - Liver Transplant Unit, AOU Città della Salute e della Scienza di Torino), et al

About Bridge to Life Ltd
Bridge to Life Ltd is a market leader in organ preservation solutions, offering premier products such as Belzer UW, EasiSlush and the VitaSmart¹ Machine Perfusion System. With a strong focus on product quality, innovation and accessibility, the company serves and partners with leading Transplant Centers and Organ Procurement Offices (OPO) globally.

^{1 VitaSmart is CE Marked and available for sale in several markets outside of the United States. VitaSmart is not approved for sale in the US. The company successfully completed its pivotal, multicenter, randomized clinical study in the US in 2023 and expects to submit its Premarket Approval submission to FDA later this year.}

View original content:https://www.prnewswire.co.uk/news-releases/italian-studies-confirm-safety-of-hope-hypothermic-oxygenated-perfusion-for-liver-transplantation-and-value-of-hope-in-identifying-biomarkers-for-assessing-liver-viability-302254350.html